Looking both ways

Looking both ways: the Jamieson Memorial Lecture, 2006.

The Jamieson Memorial Lecture, delivered annually to the Neurosurgical Society of Australasia, commemorates the life and work of a leading Australasian neurosurgeon, Dr Kenneth Grant Jamieson (1925-1976), of Melbourne and Brisbane. He was the first specialist neurosurgeon to be appointed to the Brisbane General Hospital, the Brisbane Children's Hospital and the newly established Princess Alexan...

Looking both ways: new research on old theories

times of excitement when an unexpected discovery spurs one to more exploration and discovery. One of his such moments was that despite its three macroscopical anatomical divisions and 10 histological, connective tissue-defined segments, the mouse epididymis showed unexpectedly six major clusters of gene activity. The location of gene expression did not correspond to the histological segments, a...

Barcan Both Ways

New ways of looking at experimental phasing.

In the original work by Blow and Crick, experimental phasing was formulated as a least-squares problem. For good data on good derivatives this approach works reasonably well, but we now attempt to extract more information from poorer data than in the past. As in many other crystallographic problems, the assumptions underlying the use of least squares for phasing are not satisfied, particularly ...

Twenty Ways of Looking at a Centrosome

Any serious understanding of how centrosomes work will depend on having a complete parts list and knowledge of how the parts fit together. One of the big suc-The Centrosome in Cell Replication cesses for assembling this parts list was the identifica-and Early Development tion of ␥-tubulin and the realization of its key role in Edited by R.E. Palazzo and G.P. Schatten microtubule nucleation. ␥-t...